I use Emacs for taking notes and project management using Remember-Mode and Org-Mode (see my blog entries Capturing and More. However, if I am working in Excel or reading a pdf , More and I want to make a note or I suddenly have a thought about a feature that I want to add to my model, I have to jump to Emacs,hit some keys, enter the note or the task and navigate back to the program I was working in.

Not much of a hassle, but inefficient as it really interrupts my work flow too much.

No problem,